Microscopic Observation Drug Susceptibility Assay for Rapid Diagnosis of Lymph Node Tuberculosis and Detection of Drug Resistance

نویسندگان

  • Daniela E. Kirwan
  • Cesar Ugarte-Gil
  • Robert H. Gilman
  • Luz Caviedes
  • Hasan Rizvi
  • Eduardo Ticona
  • Gonzalo Chavez
  • José Luis Cabrera
  • Eduardo D. Matos
  • Carlton A. Evans
  • David A. J. Moore
  • Jon S. Friedland
  • G. A. Land
چکیده

In this study, 132 patients with lymphadenopathy were investigated. Fifty-two (39.4%) were diagnosed with tuberculosis (TB). The microscopic observation drug susceptibility (MODS) assay provided rapid (13 days), accurate diagnosis (sensitivity, 65.4%) and reliable drug susceptibility testing (DST). Despite its lower sensitivity than that of other methods, its faster results and simultaneous DST are advantageous in resource-poor settings, supporting the incorporation of MODS into diagnostic algorithms for extrapulmonary TB.

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عنوان ژورنال:

دوره 54  شماره 

صفحات  -

تاریخ انتشار 2016